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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560341Generated: October 26, 2026

3-Chlorobenzoic Acid → (1S,2S,5R)-2-[(3-Chloro-benzoylamino)-methyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic Acid Tert-butyl Ester

https://huagongshe.com/reaction/560341

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chlorobenzoic AcidHCID 447—
Reactanttert-butyl (1S,2S,5R)-2-(aminomethyl)-3-azabicyclo(3.1.0)hexane-3-carboxylateHCID 59444330—
Product(1S,2S,5R)-2-[(3-Chloro-benzoylamino)-methyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic Acid Tert-butyl EsterHCID 66998756—

Reaction Steps

prepared by reaction of (1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester with 3-Chloro-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-0153099cbc29467eab87b029257c4fdf
Source noteuspto-grants-2011_11