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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560355Generated: October 29, 2026

2-(Trifluoromethyl)benzoic acid → Benzofuran-4-carboxylic acid[(1s,2s,5r)-3-(2-trifluoromethyl-benzoyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amide

https://huagongshe.com/reaction/560355

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzoic acidHCID 9899—
ReactantBenzofuran-4-carboxylic acid[(1s,2s,5r)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amideHCID 66998521—
ProductBenzofuran-4-carboxylic acid[(1s,2s,5r)-3-(2-trifluoromethyl-benzoyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amideHCID 66998359—

Reaction Steps

prepared by reaction of benzofuran-4-carboxylic acid[(1S,2S,5R)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide with 2-trifluoromethyl-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-118e39e8fc934a7693344c4a8ab2df60
Source noteuspto-grants-2011_11