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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560357Generated: October 30, 2026

3-(Trifluoromethyl)benzoic acid → Benzofuran-4-carboxylic acid[(1s,2s,5r)-3-(3-trifluoromethyl-benzoyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amide

https://huagongshe.com/reaction/560357

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzoic acidHCID 9963—
ReactantBenzofuran-4-carboxylic acid[(1s,2s,5r)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amideHCID 66998521—
ProductBenzofuran-4-carboxylic acid[(1s,2s,5r)-3-(3-trifluoromethyl-benzoyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amideHCID 66998826—

Reaction Steps

prepared by reaction of benzofuran-4-carboxylic acid[(1S,2S,5R)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide with 3-trifluoromethyl-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-2cdf75efa5214c80bff0a16941a0ee1f
Source noteuspto-grants-2011_11