反应详情

A mixture of 3 g (6.84 mmoles) of α-[3-(trifluoromethyl)benzylamino]-1-benzylindole 3-acetic acid, 3.4 ml (6.80 mmoles) of 2N NaOH, and 100 ml of MeOH was warmed until a solution was obtained (one to two hours). The solvent was evaporated. The residue was dried in a vacuum oven at 66° for 70 hours giving 2.70 (86%) of the title compound as an orange solid, m.p. 210°-215°.

1. temperaturewas warmed until a solution
2. customwas obtained (one to two hours)
3. customThe solvent was evaporated
4. customThe residue was dried in a vacuum oven at 66° for 70 hours