HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Sodium alpha-[3-(trifluoromethyl)benzylamino]-1-benzylindole-3-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 53973377 | HCID 53973377 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Sodium alpha-[3-(trifluoromethyl)benzylamino]-1-benzylindole-3-acetate | HCID 67883690 | — |
Reaction Steps
A mixture of 3 g (6.84 mmoles) of α-[3-(trifluoromethyl)benzylamino]-1-benzylindole 3-acetic acid, 3.4 ml (6.80 mmoles) of 2N NaOH, and 100 ml of MeOH was warmed until a solution was obtained (one to two hours). The solvent was evaporated. The residue was dried in a vacuum oven at 66° for 70 hours giving 2.70 (86%) of the title compound as an orange solid, m.p. 210°-215°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05245046 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-117b19d4882f4413bce8c78046c64c8c |
| Source note | uspto-grants-1993_09 |