反应详情

60 mg (0.16 mmol) of the compound from Example 6 were introduced into 2 ml of dichloromethane at 0° C., 40.7 mg (0.17 mmol) of 70% pure meta-chloroperbenzoic acid were added, and the mixture was stirred at RT overnight. It was concentrated, and the residue was purified by preparative HPLC (RP18 column; mobile phase: acetonitrile/water gradient with addition of 0.1% formic acid) to result in 29 mg (46% of theory) of the title compound as mixture of diastereomers.

1. concentrationIt was concentrated
2. customthe residue was purified by preparative HPLC (RP18 column; mobile phase: acetonitrile/water gradient with addition of 0.1% formic acid)