HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-{1-Cyclopropyl-1-[4-(trifluoromethyl)phenyl]ethyl}-7-[(methylsulfanyl)methyl]-1H-indole → 3-{1-Cyclopropyl-1-[4-(trifluoromethyl)phenyl]ethyl}-7-[(methylsulfonyl)methyl]-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-{1-Cyclopropyl-1-[4-(trifluoromethyl)phenyl]ethyl}-7-[(methylsulfanyl)methyl]-1H-indole | HCID 58392190 | — |
| Reactant | 3-[1-(4-Chlorophenyl)-1-cyclopropylethyl]-7-[(methylsulfonyl)methyl]-1H-indole | HCID 58392388 | — |
| Product | 3-{1-Cyclopropyl-1-[4-(trifluoromethyl)phenyl]ethyl}-7-[(methylsulfonyl)methyl]-1H-indole | HCID 58392468 | — |
Reaction Steps
The title compound was prepared starting from 153 mg (0.39 mmol) of the compound from Example 185 in analogy to the synthesis of the compound from Example 209. 63 mg (38% of theory) of the target compound were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063234B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-7ad6a9d6426d4d11926fc1e4a73e5a62 |
| Source note | uspto-grants-2011_11 |