Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 2-fluoro-N-(4-morpholinobutyl)-4-nitroaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1,2-Difluoro-4-nitrobenzene | HCID 123053 | — |
| 반응물 | 4-(Morpholin-4-yl)butan-1-amine | HCID 233611 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2-fluoro-N-(4-morpholinobutyl)-4-nitroaniline | HCID 117966064 | — |
반응 단계
A suspension of 4-morpholinobutan-1-amine (0.63 g, 4.00 mmol), 1,2-difluoro-4-nitrobenzene (0.64 g, 4.00 mmol) and K2CO3 (1.10 g, 8.00 mmol) in acetonitrile (20 mL) was stirred at rt for 19 h under N2, then filtered. The filtrate was concentrated in vacuo to give the crude product for the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434695B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-3a675810b1134632b765617e574da304 |
| 출처 메모 | uspto-grants-2016_09 |