反应详情

To a solution of 1-chloro-4-(2-methoxyethoxy)-2-methylbenzene from the previous step (1 eq.) in carbon tetrachloride (0.02 M) was added N-bromosuccinimide (1 eq.) and a few crystals of AIBN (1.1 eq.). The resulting mixture was irradiated with sunlamp at reflux for 1 h. The insolubles were removed via filtration and the filtrate was concentrated in vacuo to furnish the title compound.

1. customThe resulting mixture was irradiated with sunlamp
2. temperatureat reflux for 1 h
3. customThe insolubles were removed via filtration
4. concentrationthe filtrate was concentrated in vacuo