HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Fluoro-4-nitrophenyl)-(3-imidazol-1-ylpropyl)amine → HCID 28993591, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Fluoro-4-nitrophenyl)-(3-imidazol-1-ylpropyl)amine | HCID 18003903 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 28993591 | HCID 28993591 | 94% |
Reaction Steps
To a solution of N-(3-(1H-imidazol-1-yl)propyl)-2-fluoro-4-nitroaniline (1.20 g, 4.54 mmol) in THF (20 mL) was added catalyst Pd/C (0.30 g). The reaction mixture was stirred at rt under H2 overnight. The mixture was filtered, and the filtrate was concentrated in vacuo to give the title compound as yellow oil (1.00 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434695B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-79030226c78847ccb382db9e40140f39 |
| Source note | uspto-grants-2016_09 |