HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 131736911, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 90031330 | HCID 90031330 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 131736911 | HCID 131736911 | — |
Reaction Steps
A mixture of N-(2-(1H-indol-2-yl)ethyl)-2-fluoro-4-nitroaniline (2.32 g, 7.75 mmol) and Pd/C (0.60 g) in mixed solvents of EtOAc (25 mL) and MeOH (25 mL) was stirred at rt under H2 overnight. The mixture was then filtered, and the filtrate was concentrated in vacuo to give the crude product, which was used for next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434695B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-4d90b27a0663457da580a165c779b457 |
| Source note | uspto-grants-2016_09 |