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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56194Generated: October 30, 2026

Ethyl Acetate → HCID 131736911, compound

https://huagongshe.com/reaction/56194

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
ReactantHCID 90031330HCID 90031330—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 131736911HCID 131736911—

Reaction Steps

A mixture of N-(2-(1H-indol-2-yl)ethyl)-2-fluoro-4-nitroaniline (2.32 g, 7.75 mmol) and Pd/C (0.60 g) in mixed solvents of EtOAc (25 mL) and MeOH (25 mL) was stirred at rt under H2 overnight. The mixture was then filtered, and the filtrate was concentrated in vacuo to give the crude product, which was used for next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434695B2
Source datasetuspto-grants-2016_09
ORD IDord-4d90b27a0663457da580a165c779b457
Source noteuspto-grants-2016_09