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HRID562001

反应详情

EQUATION

反应方程式

HRID 562001 的结构方程式

REACTANTS

反应物

6
结构：O=C1CCC(=O)N1Cl
HCID31398

N-Chlorosuccinimide

C4H4ClNO2

结构：Clc1cc(I)ccc1I
HCID53406555

2-Chloro-1,4-diiodobenzene

C6H3ClI2

结构：CC(C)[C@@H](c1ncc(-c2ccc(I)cc2)[nH]1)N1C(=O)N[C@H](CCC(=O)O)C1=O
HCID57771978

未命名化合物

结构：CN(C)C(=O)COc1ccc([C@@H](NC(=O)OC(C)(C)C)C(=O)O)cc1
HCID66815126

未命名化合物

结构：CC[Mg]Br
HCID178418443

未命名化合物

结构：Cc1nc([C@H]([C@@H](C)c2ccccc2)N2C(=O)N[C@H](CC3CC3)C2=O)[nH]c1-c1ccc(I)cc1F
HCID178432851

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc([C@H]([C@@H](C)c2ccccc2)N2C(=O)N[C@H](c3ccc(OCCO)cc3)C2=O)[nH]c1-c1ccc(I)cc1Cl
HCID178432848

未命名化合物

PROCEDURE

实验过程

Prepared by the same method as described in example 1 except that (i) in step 94-A 2-chloro-1,4-diiodo-benzene was used in place of 2-fluoro-1,4-diiodo-benzene; (ii) in step 93-B ethylmagnesium bromide was used in place of methylmagnesium chloride and (iii) chlorination of the 5-position of the imidazole ring with N-chlorosuccinimide in step 94-F was omitted. HR-MS: calcd for C30H28ClIN4O4 [M+H+] 671.0917. Found 671.0917.

WORKUP

后处理

  1. customPrepared by the same method