Piperidine → 6-Amino-2-[(1-methylethyl)oxy]-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one

HRID 562789Notes

Reaction equation

HRID 562789 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[C:15]([O:16]C)=[N:14][C:13]2[C:8]1=[N:9][C:10]([O:19][CH:20]([CH3:22])[CH3:21])=[N:11][C:12]=2[NH2:18].[NH:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[NH2:18][C:12]1[N:11]=[C:10]([O:19][CH:20]([CH3:22])[CH3:21])[N:9]=[C:8]2[C:13]=1[NH:14][C:15](=[O:16])[N:7]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][N:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 592526339-(5-Chloropentyl)-2-[(1-methylethyl)oxy]-8-(methyloxy)-9H-purin-6-amine

Product 1

HCID 592525796-Amino-2-[(1-methylethyl)oxy]-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one

Procedure

Prepared similarly to Example 29 from 9-(5-chloropentyl)-2-[(1-methylethyl)oxy]-8-(methyloxy)-9H-purin-6-amine and piperidine.

Sources & evidence

ORD record
ord-3dd5e44b4fd54a768e17800d72e716ea
Source dataset
uspto-grants-2011_11
Patent number
US08067426B2

Reaction notes

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