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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562892Generated: November 2, 2026

N-bromobutanimide → 5-Bromo-3-fluoro-2-hydroxybenzonitrile

https://huagongshe.com/reaction/562892

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-bromobutanimideHCID 67184—
Reactant3-Fluoro-2-hydroxybenzonitrileHCID 50998841—
SolventAcetonitrileHCID 6342—
Product5-Bromo-3-fluoro-2-hydroxybenzonitrileHCID 58076937—

Reaction Steps

3-Fluoro-2-hydroxybenzonitrile and N-bromosuccinimide were stirred at room temperature in acetonitrile to obtain 5-bromo-3-fluoro-2-hydroxybenzonitrile. EI: 215, 217.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067446B2
Source datasetuspto-grants-2011_11
ORD IDord-29fc5b8a6ddf45a780c965c9286c415e
Source noteuspto-grants-2011_11