Methanesulfonic Acid → HCID 25195527, compound

HRID 563052Notes

Reaction equation

HRID 563052 reaction equation
[NH2:1][C@@H:2]([CH2:6][O:7][C:8]([O:10][C:11]1[C:16]([CH:17]([CH3:19])[CH3:18])=[CH:15][CH:14]=[CH:13][C:12]=1[CH:20]([CH3:22])[CH3:21])=[O:9])[C:3]([OH:5])=[O:4].[CH3:23][S:24]([OH:27])(=[O:26])=[O:25]>O>[S:24]([OH:27])(=[O:26])(=[O:25])[CH3:23].[NH2:1][C@@H:2]([CH2:6][O:7][C:8]([O:10][C:11]1[C:16]([CH:17]([CH3:18])[CH3:19])=[CH:15][CH:14]=[CH:13][C:12]=1[CH:20]([CH3:22])[CH3:21])=[O:9])[C:3]([OH:5])=[O:4]

Participants

4

Reactant 2

HCID 6395Methanesulfonic AcidHCID 11716529HCID 11716529, compound

Product 1

HCID 25195527HCID 25195527, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a suspension of compound (3) (4.44 g, 14.3 mmol) in H2O (100 mL) was added methanesulfonic acid (0.93 mL, 14.3 mmol). The resulting mixture was stirred at room temperature until the solid had completely dissolved. The solution was then frozen and lyophilized to afford the desired product as a light pinkish solid.

Workup

  1. dissolutionhad completely dissolved
  2. temperatureThe solution was then frozen

Sources & evidence

ORD record
ord-4ff5210a100244faafa6b131919b4b2c
Source dataset
uspto-grants-2011_11
Patent number
US08067455B2

Reaction notes

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