HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-1H-1,2,4-triazol-3-amine → 3-(1-(4-Fluorophenyl)-1H-indazol-5-yl)-N-(1-methyl-1H-1,2,4-triazol-3-yl)-3-phenylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-1H-1,2,4-triazol-3-amine | HCID 566503 | — |
| Reactant | 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-3-phenylpropanoic acid | HCID 67005806 | — |
| Product | 3-(1-(4-Fluorophenyl)-1H-indazol-5-yl)-N-(1-methyl-1H-1,2,4-triazol-3-yl)-3-phenylpropanamide | HCID 59252895 | 11% |
Reaction Steps
Example 137 was prepared from 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-3-phenylpropanoic acid (50 mg, 0.14 mmol) and 1-methyl-1H-1,2,4-triazol-3-amine using General Coupling Method A to give 7 mg (11% yield). MS found: (M+H)+=441.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067447B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-f9ad09484fc2457c842682e188c76e72 |
| Source note | uspto-grants-2011_11 |