HRID563416

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID19909

2-Amino-1,3,4-thiadiazole

C2H3N3S

$结构：CC(C)/C=C(\c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)C(=O)O$

HCID67005634

未命名化合物

PRODUCTS

生成物

$结构：CC(C)/C=C(\c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)C(=O)Nc1nncs1$

HCID59252812

未命名化合物

收率 25%

PROCEDURE

实验过程

Example 139 was prepared from (E)-3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2,2,5-trimethylhex-3-enoic acid (105 mg, 0.29 mmol) and 1,3,4-thiadiazol-2-amine using General Coupling Method B to give 30 mg (25% yield). MS found: (M+H)+=450.

WORKUP

后处理

customto give 30 mg (25% yield)