HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 59252795, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 24937871 | HCID 24937871 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 59252795 | HCID 59252795 | 7.3% |
Reaction Steps
Example 155 was prepared from 3-(1,3,4-thiadiazol-2-ylamino)-2-((1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methyl)-2-methyl-3-oxopropyl acetate (24 mg, 0.168 mmol) by treating with 1N HCl in CH3CN and heating for 1 hr at reflux. The product was purified by HPLC to give 6 mg of desired product. MS found: (M+H)+=48.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067447B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-deddbcc5058147ac8b7624ba5c035d3e |
| Source note | uspto-grants-2011_11 |