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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563441Generated: October 29, 2026

Hydrochloric Acid → HCID 59252795, compound

https://huagongshe.com/reaction/563441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 24937871HCID 24937871—
SolventAcetonitrileHCID 6342—
ProductHCID 59252795HCID 592527957.3%

Reaction Steps

Example 155 was prepared from 3-(1,3,4-thiadiazol-2-ylamino)-2-((1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methyl)-2-methyl-3-oxopropyl acetate (24 mg, 0.168 mmol) by treating with 1N HCl in CH3CN and heating for 1 hr at reflux. The product was purified by HPLC to give 6 mg of desired product. MS found: (M+H)+=48.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067447B2
Source datasetuspto-grants-2011_11
ORD IDord-deddbcc5058147ac8b7624ba5c035d3e
Source noteuspto-grants-2011_11