Benzyl chloroformate → (2-Bromo-5-trifluoromethyl-benzyl)-ethyl-carbamic acid benzyl ester

HRID 563533Notes

Reaction equation

[Br:1][C:2]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:3]=1[CH2:4][NH:5][CH2:6][CH3:7].Cl[C:17]([O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:18]>>[CH2:20]([O:19][C:17](=[O:18])[N:5]([CH2:4][C:3]1[CH:8]=[C:9]([C:12]([F:13])([F:14])[F:15])[CH:10]=[CH:11][C:2]=1[Br:1])[CH2:6][CH3:7])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

Reactant 2

HCID 10387Benzyl chloroformate

HCID 66603999(2-Bromo-5-trifluoromethyl-benzyl)-ethyl-amine

Product 1

HCID 66604198(2-Bromo-5-trifluoromethyl-benzyl)-ethyl-carbamic acid benzyl ester

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2-bromo-5-trifluoromethyl-benzyl)-ethyl-amine and benzyl chloroformate.

Workup

customPrepared

Sources & evidence

ORD record: ord-7143ab1b72954fd4b9ffa4a654332765
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08067445B2

Reaction notes

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