化工社化工社 化学情報印刷レポート · 研究参考用
2-Bromo-5-nitrobenzoic acid → (2-Bromo-5-nitrophenyl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Bromo-5-nitrobenzoic acid | HCID 243025 | — |
| 反応物 | Borane;tetrahydrofuran | HCID 2723981 | — |
| 生成物 | (2-Bromo-5-nitrophenyl)methanol | HCID 18671373 | — |
反応手順
To 2-bromo-5-nitrobenzoic acid (5 g, 20 mmol) at 0° C. was added borane tetrahydrofuran complex (1 M in THF; 200 mL, 200 mmol), and the reaction was stirred at room temperature overnight. The mixture was quenched with 1N aqueous HCl to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08067445B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-10610fa9968e4d3ba8c45c75675bc868 |
| 出典メモ | uspto-grants-2011_11 |