Phosgene → 3,5-Dichlorobenzyl Chloroformate

HRID 563579Notes

Reaction equation

HRID 563579 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([Cl:10])[CH:9]=1)[CH2:5][OH:6].[C:11](Cl)([Cl:13])=[O:12]>C(Cl)Cl>[Cl:13][C:11]([O:6][CH2:5][C:4]1[CH:3]=[C:2]([Cl:1])[CH:9]=[C:8]([Cl:10])[CH:7]=1)=[O:12]

Participants

4

Reactant 2

HCID 6371PhosgeneHCID 432363,5-Dichlorobenzylic alcohol

Product 1

HCID 133055323,5-Dichlorobenzyl Chloroformate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To 3,5-dichlorobenzyl alcohol (0.201 g, 1.06 mmol) in CH2Cl2 (0.5 mL) was added phosgene (20% in toluene; 0.42 mL, 0.79 mmol), and the mixture was stirred at room temperature for 30 minutes to give the title compound, which was used directly in the next step.

Sources & evidence

ORD record
ord-653d9b24318b4ce58c5b4d26d8b885b1
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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