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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563604Generated: October 30, 2026

2-(3-Bromo-4-methoxy-phenyl)-2-methyl-propionic acid ethyl ester → 2-(2'-Formyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-2-methyl-propionic acid ethyl ester

https://huagongshe.com/reaction/563604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Bromo-4-methoxy-phenyl)-2-methyl-propionic acid ethyl esterHCID 57458805—
Reactant2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzaldehydeHCID 86640534—
Product2-(2'-Formyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-2-methyl-propionic acid ethyl esterHCID 86651115—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 2-(3-bromo-4-methoxy-phenyl)-2-methyl-propionic acid ethyl ester and 2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-027682b6a859416185b21e7c20ce3550
Source noteuspto-grants-2011_11