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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563610Generated: October 31, 2026

HCID 44159648, compound → HCID 54673387, compound

https://huagongshe.com/reaction/563610

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 44159648HCID 44159648—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 54673387HCID 54673387—

Reaction Steps

{2′-[(Benzyloxycarbonyl-cyclopropyl-amino)-methyl]-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid (0.054 g, 0.10 mmol) and 10% palladium on carbon (17.5 g) were combined in MeOH (2 mL) and stirred under a balloon of H2 at room temperature for 1 hour. The mixture was filtered and concentrated to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-62c73db20b704abcb9f85daf3dd22c70
Source noteuspto-grants-2011_11