HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 44159648, compound → HCID 54673387, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 44159648 | HCID 44159648 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 54673387 | HCID 54673387 | — |
Reaction Steps
{2′-[(Benzyloxycarbonyl-cyclopropyl-amino)-methyl]-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid (0.054 g, 0.10 mmol) and 10% palladium on carbon (17.5 g) were combined in MeOH (2 mL) and stirred under a balloon of H2 at room temperature for 1 hour. The mixture was filtered and concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067445B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-62c73db20b704abcb9f85daf3dd22c70 |
| Source note | uspto-grants-2011_11 |