HRID563677

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCN(Cc1cc(C(=O)O)ccc1Br)C(=O)OCc1ccccc1

HCID57419864

未命名化合物

结构：CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1

HCID58120060

[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]acetic acid ethyl ester

C17H25BO5

PRODUCTS

生成物

结构：CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(=O)O)cc2CN(CC)C(=O)OCc2ccccc2)c1

HCID54674329

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 3-[(benzyloxycarbonyl-ethyl-amino)-methyl]-4-bromo-benzoic acid and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester. M+H is 506.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-eee2d4fd3ba3495cbf08131f2075c95f
来源数据集: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08067445B2
来源说明: uspto-grants-2011_11

反应 SMILES

[CH2:1]([O:8][C:9]([N:11]([CH2:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1Br)[C:18]([OH:20])=[O:19])[CH2:12][CH3:13])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:25]([O:27][C:28](=[O:47])[CH2:29][C:30]1[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[C:32](B2OC(C)(C)C(C)(C)O2)[CH:31]=1)[CH3:26]>>[CH2:1]([O:8][C:9]([N:11]([CH2:14][C:15]1[CH:16]=[C:17]([C:18]([OH:20])=[O:19])[CH:21]=[CH:22][C:23]=1[C:32]1[CH:31]=[C:30]([CH2:29][C:28]([O:27][CH2:25][CH3:26])=[O:47])[CH:35]=[CH:34][C:33]=1[O:36][CH3:37])[CH2:12][CH3:13])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1