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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563682Generated: October 30, 2026

Cyclopropanecarbonyl chloride → {5-Chloro-2'-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4'-fluoro-biphenyl-3-yl}-acetic acid ethyl ester

https://huagongshe.com/reaction/563682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbonyl chlorideHCID 77637—
Reactant(5-Chloro-2'-ethylaminomethyl-4'-fluoro-biphenyl-3-yl)-acetic acid ethyl esterHCID 58148881—
Product{5-Chloro-2'-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4'-fluoro-biphenyl-3-yl}-acetic acid ethyl esterHCID 58149054—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (5-chloro-2′-ethylaminomethyl-4′-fluoro-biphenyl-3-yl)-acetic acid ethyl ester and cyclopropanecarbonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-5d5c884663a8405580402ec938968162
Source noteuspto-grants-2011_11