p-Chlorophenoxyacetyl chloride → [2'-({[2-(4-Chloro-phenoxy)-acetyl]-ethyl-amino}-methyl)-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester

Participants

Role	Name	HCID	Charge
Reactant	p-Chlorophenoxyacetyl chloride	HCID 77771	—
Reactant	[4'-(6-Ethoxy-pyridin-3-yl)-2'-ethylaminomethyl-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester	HCID 58148820	—
Product	[2'-({[2-(4-Chloro-phenoxy)-acetyl]-ethyl-amino}-methyl)-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester	HCID 58149310	—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: [4′-(6-ethoxy-pyridin-3-yl)-2′-ethylaminomethyl-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester and 4-chlorophenoxyacetyl chloride.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08067445B2
Source dataset	uspto-grants-2011_11
ORD ID	ord-c54bce9e6b294934be368d6b86dddc1f
Source note	uspto-grants-2011_11