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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563768Generated: October 30, 2026

2-Chloro-5-methyl-1,3-benzoxazole → {6-Methoxy-2'-[(5-methyl-benzooxazol-2-ylamino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester

https://huagongshe.com/reaction/563768

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methyl-1,3-benzoxazoleHCID 9989607—
Reactant(2'-Aminomethyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl esterHCID 66606861—
Product{6-Methoxy-2'-[(5-methyl-benzooxazol-2-ylamino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl esterHCID 66608088—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-aminomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and 2-chloro-5-methyl-benzooxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-4e027681afe2455a9a15a0d3e510254c
Source noteuspto-grants-2011_11