Hydrochloric Acid → methyl 2-(5-bromo-2-fluorophenyl)acetate

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a solution of (5-bromo-2-fluoro-phenyl)-acetic acid (2.3 mmol) in MeOH (15 mL) was added 4N HCl in 1,4-dioxane (2 mL), and the reaction was stirred at 90° C. for 2 hours. The mixture was concentrated, and the residue was purified by silica gel chromatography to give the title compound.

Herkunft & Nachweise