Ammonia → 2-Amino-3,5-dinitropyridine

HRID 564000Notes

Reaction equation

HRID 564000 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=1.[NH3:14]>C(O)C>[NH2:14][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 757382-Chloro-3,5-dinitropyridine

Product 1

HCID 5043402-Amino-3,5-dinitropyridine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 25 g 2-Chloro-3,5-dinitropyridine in 190 ml ethanol were added dropwise 75 ml concentrated ammonia at room temperature. After stirring for 1 hour (hr), the mixture was cooled in an ice bath. The product was isolated by filtration and washed with cold water.

Workup

  1. temperaturethe mixture was cooled in an ice bath
  2. customThe product was isolated by filtration
  3. washwashed with cold water

Sources & evidence

ORD record
ord-f591333097c54192914a348203b76141
Source dataset
uspto-grants-2011_11
Patent number
US08067599B2

Reaction notes

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