5-(5-Fluoro-pyridin-2-ylmethoxy)-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one → 5-((5-fluoropyridin-2-yl)methoxy)pyridazin-3(2H)-one

HRID 564078노트

반응식

HRID 564078 반응식
ClC1C=CC(COC2C=NNC(=O)C=2)=NC=1.[F:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:24][O:25][C:26]2[CH:31]=[N:30][N:29](C3CCCCO3)[C:28](=[O:38])[CH:27]=2)=[N:22][CH:23]=1>>[F:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:24][O:25][C:26]2[CH:31]=[N:30][NH:29][C:28](=[O:38])[CH:27]=2)=[N:22][CH:23]=1

참가 물질

3

반응물 2

HCID 580921945-(5-Fluoro-pyridin-2-ylmethoxy)-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-oneHCID 670071055-(5-chloro-pyridin-2-ylmethoxy)-2H-pyridazin-3-one

생성물 1

HCID 580922585-((5-fluoropyridin-2-yl)methoxy)pyridazin-3(2H)-one

실험 절차

5-(5-Fluoro-pyridin-2-ylmethoxy)-2H-pyridazin-3-one is prepared following preparation 18b from 800 mg (2.62 mmol) 5-(5-fluoro-pyridin-2-ylmethoxy)-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one.

출처 및 근거

ORD 기록
ord-b3e44eb13001419e9e045e08f7a72c26
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08067590B2

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