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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 564078Generated: October 27, 2026

5-(5-Fluoro-pyridin-2-ylmethoxy)-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one → 5-((5-fluoropyridin-2-yl)methoxy)pyridazin-3(2H)-one

https://huagongshe.com/reaction/564078

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(5-Fluoro-pyridin-2-ylmethoxy)-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-oneHCID 58092194—
Reactant5-(5-chloro-pyridin-2-ylmethoxy)-2H-pyridazin-3-oneHCID 67007105—
Product5-((5-fluoropyridin-2-yl)methoxy)pyridazin-3(2H)-oneHCID 58092258—

Reaction Steps

5-(5-Fluoro-pyridin-2-ylmethoxy)-2H-pyridazin-3-one is prepared following preparation 18b from 800 mg (2.62 mmol) 5-(5-fluoro-pyridin-2-ylmethoxy)-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067590B2
Source datasetuspto-grants-2011_11
ORD IDord-b3e44eb13001419e9e045e08f7a72c26
Source noteuspto-grants-2011_11