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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 564155Generated: October 30, 2026

Piperidin-4-ol → HCID 58042809, compound

https://huagongshe.com/reaction/564155

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidin-4-olHCID 79341—
ReactantN-(1,3-benzodioxol-5-ylmethyl)-N-(2-piperidin-1-yl-2-thioxoethyl)amineHCID 10334538—
Reactant1-[2-(4-Bromomethyl-phenyl)-ethyl]-4-phenoxy-1H-pyridin-2-oneHCID 67006988—
ProductHCID 58042809HCID 58042809—

Reaction Steps

1-{2-[4-(4-Hydroxy-piperidin-1-ylmethyl)-phenyl]-ethyl}-4-phenoxy-1H-pyridin-2-one is prepared as example 16.2c from 100 mg (0.26 mmol) 1-[2-(4-bromomethyl-phenyl)-ethyl]-4-phenoxy-1H-pyridin-2-one (example 16.2b) and 105 mg (1.04 mmol) 4-hydroxy-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067590B2
Source datasetuspto-grants-2011_11
ORD IDord-e5bbebc9e37941058dbe2b5180ad3d29
Source noteuspto-grants-2011_11