HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyloxy-2(1H)-pyridone → HCID 86623692, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyloxy-2(1H)-pyridone | HCID 3607724 | — |
| Reactant | HCID 58042801 | HCID 58042801 | — |
| Reactant | 4-Benzyloxy-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one | HCID 67006842 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 86623692 | HCID 86623692 | — |
Reaction Steps
4-Benzyloxy-1-{2-oxo-2-[2-(2,2,2-trifluoro-acetyl)-2,3-dihydro-1H-isoindol-5-yl]-ethyl}-1H-pyridin-2-one is prepared following preparation 15b from 1.50 g (7.45 mmol) 4-benzyloxy-1H-pyridin-2-one and 2.28 g (7.83 mmol) 1-[5-(2-chloro-acetyl)-1,3-dihydro-isoindol-2-yl]-2,2,2-trifluoro-ethanone (see preparation 23) in DMSO as solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067590B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-c5a65ce2b605423887e367d1de48ef89 |
| Source note | uspto-grants-2011_11 |