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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 564260Generated: October 30, 2026

Trifluoroacetic acid → (E)-3-(1-phenylmethanesulfonyl-1H-pyrrol-3-yl)-acrylic acid

https://huagongshe.com/reaction/564260

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant(E)-3-(1-phenylmethanesulfonyl-1H-pyrrol-3-yl)-acrylic acid tert-butylesterHCID 66646367—
SolventDichloromethaneHCID 6344—
Product(E)-3-(1-phenylmethanesulfonyl-1H-pyrrol-3-yl)-acrylic acidHCID 66646065—

Reaction Steps

Starting materials: (E)-3-(1-phenylmethanesulfonyl-1H-pyrrol-3-yl)-acrylic acid tert-butylester (compound C2) (1.45 g), CH2Cl2 (80 ml), TFA (8 ml). Reaction conditions: room temperature, 2 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067615B2
Source datasetuspto-grants-2011_11
ORD IDord-86ca749fec8d49c388cfee24632dbb43
Source noteuspto-grants-2011_11