1-Benzylpiperidin-3-amine → N-(2-oxo-2-(1-(tetrahydro-2H-pyran-4-yl)piperidin-3-ylamino)ethyl)-3-(trifluoromethyl)benzamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Benzylpiperidin-3-amine	HCID 421694	—
Edukt	(3R)-1-benzylpyrrolidin-3-amine	HCID 1519354	—
Edukt	N-(2-oxo-2-{[1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl]amino}ethyl)-3-(trifluoromethyl)benzamide	HCID 67005250	—
Produkt	N-(2-oxo-2-(1-(tetrahydro-2H-pyran-4-yl)piperidin-3-ylamino)ethyl)-3-(trifluoromethyl)benzamide	HCID 57814104	—

Reaktionsschritte

The title compound was synthesized in similar fashion to N-(2-oxo-2-{[1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl]amino}ethyl)-3-(trifluoromethyl)benzamide whereby 1-benzylpiperidin-3-amine was substituted for (3R)-1-benzylpyrrolidin-3-amine as was isolated as a white solid.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08067457B2
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-256186d4e5d145228b54be64c9375d29
Quellennotiz	uspto-grants-2011_11