HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-methyl-1H-pyrazole-4-carbonitrile → HCID 54462403, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-methyl-1H-pyrazole-4-carbonitrile | HCID 219740 | — |
| Reactant | 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester | HCID 54119345 | — |
| Product | HCID 54462403 | HCID 54462403 | 17.9% |
Reaction Steps
Starting from 2-ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester (100 mg) and 5-amino-1-methyl-1H-pyrazole-4-carbonitrile (71 mg). Purification by column chromatography on silica eluting with 50% hexane in ethyl acetate followed by trituration with ether gave the title compound (17 mg) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169090A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-b98180c87f464b2cb1bf4fed27b72709 |
| Source note | uspto-grants-2001_01 |