HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron Trichloride → HCID 178491549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron Trichloride | HCID 25135 | — |
| Reactant | 2,6-Dimethoxypyridine-3-carbaldehyde | HCID 12269211 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178491549 | HCID 178491549 | 75% |
Reaction Steps
8.4 g (0.05 mol) 2,6-dimethoxy-nicotinaldehyde was solved in 75 ml methylene chloride. At 0° C. (0.2 mol) BCl3 as 1 molar solution in methylene chloride 200 ml was added and stirred at room temperature for 20 h. The mixture was poured on ice/water, neutralized and extracted with CH2Cl2. Evaporation of the solvent affords 5.7 g (75%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169092A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-dc92bb21c0f641ae8fa61c5407a06367 |
| Source note | uspto-grants-2001_01 |