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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 564770Generated: October 31, 2026

Aniline, p-(phenylthio)- (6CI,7CI,8CI) → 6-Chloro-4-(4-phenylthioanilino)pyrido[3,4-d]pyrimidine hydochloride

https://huagongshe.com/reaction/564770

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAniline, p-(phenylthio)- (6CI,7CI,8CI)HCID 96081—
Reactant1,6-Dichloropyrido[3,4-d]pyrimidineHCID 86756191—
Product6-Chloro-4-(4-phenylthioanilino)pyrido[3,4-d]pyrimidine hydochlorideHCID 88217004—

Reaction Steps

Prepared according to Procedure A from 4-(phenylthio)aniline (commercially available from Salor) and 1,6-dichloropyrido[3,4-d]pyrimidine; δH [2H6]-DMSO 8.94 (1H,s), 8.85 (1H,s), 8.25 (1H,s), 7.96 (2H,d), 7.24-7.49 (7H,m); m/z (M+1)+365.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06169091A
Source datasetuspto-grants-2001_01
ORD IDord-50d0935d4cd747fb86015b40fcb6fb20
Source noteuspto-grants-2001_01