HuagongsheHuagongshe Chemistry Print Report · For research reference only
Guanidine Hydrochloride → HCID 178485141, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Guanidine Hydrochloride | HCID 5742 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Ethyl 4-chloro-1-methyl-7-(3-nitrophenoxy)-2-indolecarboxylate | HCID 21194305 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178485141 | HCID 178485141 | — |
Reaction Steps
The reaction was carried out in a manner similar to Example 186 b) except for using 0.17 g (0.45 mmol) of ethyl 4-chloro-1-methyl-7-(3-nitrophenoxy)-2-indolecarboxylate, 1.30 g of guanidine hydrochloride, 0.74 g (13.6 mmol) of sodium methoxide and 30 ml of methanol. 4-Chloro-1-methyl-7-(3-nitrophenoxy)-2-indoloylguanidine was obtained in the amount of 0.06 g (34.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169107A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-228f77c9ddce459c8c0af45dc53cef33 |
| Source note | uspto-grants-2001_01 |