Stannous chloride dihydrate → HCID 178485150, compound

HRID 565049Notes

Reaction equation

HRID 565049 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]([O:11][C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=2)[CH:8]=[C:7]2[C:3]=1[CH:4]=[C:5]([C:21]([N:23]=[C:24]([NH2:27])[NH:25][CH3:26])=[O:22])[NH:6]2.O.O.[Sn](Cl)[Cl:31]>C(O)C>[ClH:1].[ClH:31].[NH2:18][C:15]1[CH:14]=[CH:13][C:12]([O:11][C:9]2[CH:8]=[C:7]3[C:3]([CH:4]=[C:5]([C:21]([N:23]=[C:24]([NH2:27])[NH:25][CH3:26])=[O:22])[NH:6]3)=[C:2]([Cl:1])[CH:10]=2)=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 178485151HCID 178485151, compound

Product 1

HCID 178485150HCID 178485150, compoundYield 66.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction was carried out in a manner similar to Example 186 c) except for using 0.24 g (0.62 mmol) of 4-chloro-1-methyl-6-(4-nitrophenoxy)-2-indoloylguanidine, 0.72 g (3.20 mmol) of tin (II) chloride dihydrate and 15 ml of ethanol. Thus, 0.089 g of 6-(4-aminophenoxy)-4-chloro-1-methyl-2-indoloylguanidine dihydrochloride was obtained.

Sources & evidence

ORD record
ord-5972a46d18504103ae74ab8eb5c73d26
Source dataset
uspto-grants-2001_01
Patent number
US06169107A

Reaction notes

Loading…