Hydrochloric Acid → HCID 23218656, compound

HRID 565197Notes

Reaction equation

HRID 565197 reaction equation
[NH2:1][CH:2]([CH:8]([CH3:10])[CH3:9])[CH:3]([OH:7])[C:4]([OH:6])=[O:5].[ClH:11].[CH3:12][CH2:13]O>>[NH2:1][CH:2]([CH:8]([CH3:10])[CH3:9])[CH:3]([OH:7])[C:4]([O:6][CH2:12][CH3:13])=[O:5].[ClH:11]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14503312HCID 14503312, compound

Product 1

HCID 23218656HCID 23218656, compound

Procedure

Treat 3-Amino-2-hydroxy-4-methylpentanoic acid (0.89 g, 6.05 mmol) (Peet, N. P. et al., J. Med. Chem., 33, 394 (1990)) in CH3CH2OH (25 mL and then 20 mL) with gaseous HCl. Concentrate and dry over KOH pellets to give the title compound.

Workup

  1. concentrationConcentrate
  2. dry with materialdry over KOH pellets

Sources & evidence

ORD record
ord-eecb4c773a3848d28ddd1f39c089564e
Source dataset
uspto-grants-2001_01
Patent number
US06172044B2

Reaction notes

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