Hydrochloric Acid → HCID 11370062, compound

HRID 565210Notes

Reaction equation

HRID 565210 reaction equation
[CH3:1][C:2]1[C:3]([CH2:19][NH:20][CH3:21])=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[N:8]=[C:7]([O:15]C)[C:6]([O:17]C)=[N:5]2.[ClH:22]>O1CCOCC1>[ClH:22].[CH3:1][C:2]1[C:3]([CH2:19][NH:20][CH3:21])=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[C:6](=[O:17])[NH:5]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 11055436HCID 11055436, compound

Product 1

HCID 11370062HCID 11370062, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

To a solution of 6-methyl-5-methylaminomethyl-7-nitro-2,3-dimethoxy-quinoxaline (0.028 g, 0.095 mmol) in dioxane (1 mL) was added aqueous HCl (1 mL). The reaction was heated to reflux for 4 hours, cooled, and filtered. The pale yellow solid was filtered and washed with methanol.

Workup

  1. temperatureThe reaction was heated
  2. temperatureto reflux for 4 hours
  3. temperaturecooled
  4. filtrationfiltered
  5. filtrationThe pale yellow solid was filtered
  6. washwashed with methanol

Sources & evidence

ORD record
ord-204281876a33435e88b684920d0bc3a4
Source dataset
uspto-grants-2001_01
Patent number
US06172065B2

Reaction notes

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