2-(4-Methoxy-phenylsulfanyl)heptanoic acid ethyl ester → HCID 18416776, compound

HRID 565332Notes

Reaction equation

HRID 565332 reaction equation
C([O:3][C:4](=[O:20])[CH:5]([S:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])C>CO.[OH-].[Na+]>[CH3:19][O:18][C:15]1[CH:14]=[CH:13][C:12]([S:11][CH:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[C:4]([OH:20])=[O:3])=[CH:17][CH:16]=1

Participants

4

Reactant 1

HCID 543572462-(4-Methoxy-phenylsulfanyl)heptanoic acid ethyl ester

Product 1

HCID 18416776HCID 18416776, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

2-(4-Methoxy-phenylsulfanyl)-heptanoic acid was prepared starting with 2-(4-methoxy-phenylsulfanyl)-heptanoic acid ethyl ester (4 g, 13.5 mmol) dissolved in methanol (300 ml) and 10 N NaOH (25 ml). The resulting reaction mixture was worked up as outlined in example 1. Yield 3 g (83%). yellow oil. MS: 267.1 (M−H)−.

Workup

  1. customThe resulting reaction mixture

Sources & evidence

ORD record
ord-7503fe6965844efca9b83df27e74af25
Source dataset
uspto-grants-2001_01
Patent number
US06172057B2

Reaction notes

Loading…