HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 69985657, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | HCID 21268115 | HCID 21268115 | — |
| Product | HCID 69985657 | HCID 69985657 | 40.3% |
Reaction Steps
This was prepared according to the procedure described in Example 67 using 1-N-t-butoxycarbonylpiperazine instead of 4-t-butoxycarbonylaminopiperidine, and 2-chloro-1-[1-(1-phenyl-4-cyclohepten-1-yl)-4-piperidinyl]benzimidazole as starting material which was prepared in Preparation 9. Overall yield was 40.3%. HCl salt was amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172067B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-02d84a6b04824c76a01f5282e123c83e |
| Source note | uspto-grants-2001_01 |