Benzhydrol → 4-(Diphenylmethoxy)butyl chloride
Reaction equation
[CH:1]([OH:14])([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:15][CH2:16][CH2:17][CH2:18][CH2:19]O>>[C:2]1([CH:1]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[O:14][CH2:19][CH2:18][CH2:17][CH2:16][Cl:15])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
Starting with benzhydrol and 4-chloro-1-butanol, the procedure of Reference Example 15 was otherwise repeated to provide the title compoun. Yield 90%.
Workup
- customto provide the title compoun
Sources & evidence
- ORD record
- ord-c7415e29d2004a4991690bc57ebaf02d
- Source dataset
- uspto-grants-2001_01
- Patent number
- US06172085B2
Reaction notes
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