Piperazine → 1-[4-(Diphenylmethoxy)butyl]piperazine
Reaction equation
[C:1]1([CH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[O:8][CH2:9][CH2:10][CH2:11][CH2:12]Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[C:1]1([CH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[O:8][CH2:9][CH2:10][CH2:11][CH2:12][N:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1Participants
3
Procedure
Using 4-(diphenylmethoxy)butyl chloride and piperazine, the procedure of Reference Example 16 was otherwise repeated to provide the title compoud.
Workup
- customto provide the title compoud
Sources & evidence
- ORD record
- ord-29b41838d8be46d4be21186a47720ca9
- Source dataset
- uspto-grants-2001_01
- Patent number
- US06172085B2
Reaction notes
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