Fluoren-9-ol → 4-[(9-Fluorenyl)oxy]piperidine

HRID 565672Notes

Reaction equation

HRID 565672 reaction equation
[CH:1]1[C:13]2[CH:12]([OH:14])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[NH:15]1[CH2:20][CH2:19][CH:18](O)[CH2:17][CH2:16]1>>[CH:1]1[C:13]2[CH:12]([O:14][CH:18]3[CH2:19][CH2:20][NH:15][CH2:16][CH2:17]3)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 74318Fluoren-9-olHCID 79341Piperidin-4-ol

Product 1

HCID 221109894-[(9-Fluorenyl)oxy]piperidineYield 38%

Procedure

Using 9-fluorenol and 4-piperidinol, the procedure of Reference Example 23 was otherwise repeated to provide the title compound. Yield 38%.

Sources & evidence

ORD record
ord-6b625abd351143d295b3544f60a128de
Source dataset
uspto-grants-2001_01
Patent number
US06172085B2

Reaction notes

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