HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22111032, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 22111033 | HCID 22111033 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 22111032 | HCID 22111032 | 53% |
Reaction Steps
The 1-[(5-amino-2,3-dihydro-2,4,6,7-tetramethylbenzofuran-2-yl)methyl]-N-benzyl-N-(3,3-diphenylpropyl)-4-piperidinamine obtained above (1.0 g) was treated with 4N HCl solution in ethanol and the resulting trihydrochloride was recrystallized from ethanol/diethyl ether to provide 0.65 g of the title compound. Yield 53%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172085B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-530a8c74fec341ab8aaac9d4bbbc723b |
| Source note | uspto-grants-2001_01 |