HRID565706

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10850590

未命名化合物

HCID22111110

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(NC2CCN(CC3(C)Cc4c(C)c(N)c(C)c(C)c4O3)CC2)c2ccc(OC)cc2)cc1

HCID22111111

未命名化合物

收率 43%

PROCEDURE

实验过程

Starting with 2-bromomethyl-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamine and N-[bis(4-methoxyphenyl)methyl]-4-piperidinamine, the procedure of Example 53 was otherwise repeated to provide the title compound. Yield 43%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3b6f516591944037a20125d977bcd5c3
来源数据集: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06172085B2
来源说明: uspto-grants-2001_01

反应 SMILES

Br[CH2:2][C:3]1([CH3:16])[CH2:7][C:6]2[C:8]([CH3:15])=[C:9]([NH2:14])[C:10]([CH3:13])=[C:11]([CH3:12])[C:5]=2[O:4]1.[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([CH:25]([C:33]2[CH:38]=[CH:37][C:36]([O:39][CH3:40])=[CH:35][CH:34]=2)[NH:26][CH:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)=[CH:21][CH:20]=1>>[NH2:14][C:9]1[C:10]([CH3:13])=[C:11]([CH3:12])[C:5]2[O:4][C:3]([CH2:2][N:30]3[CH2:31][CH2:32][CH:27]([NH:26][CH:25]([C:22]4[CH:21]=[CH:20][C:19]([O:18][CH3:17])=[CH:24][CH:23]=4)[C:33]4[CH:34]=[CH:35][C:36]([O:39][CH3:40])=[CH:37][CH:38]=4)[CH2:28][CH2:29]3)([CH3:16])[CH2:7][C:6]=2[C:8]=1[CH3:15]