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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565739Generated: October 28, 2026

Ammonia → N-(3-Chlorophenyl)benzenemethanamine

https://huagongshe.com/reaction/565739

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 86756217HCID 86756217—
SolventChloroformHCID 6212—
ProductN-(3-Chlorophenyl)benzenemethanamineHCID 1150678296.7%

Reaction Steps

Next, (+)-(3-chlorophenyl)phenylmethylamine (+)tartrate (4.28 g) was suspended in chloroform (40 ml), and 28%-aqueous ammonia was added thereto to neutralize the mixture. Thereafter, the chloroform layer was separated therefrom. The extract was dried over anhydrous magnesium sulfate, and the solvent was removed by evaporation in vacuo, to give (+)-(3-chlorophenyl)phenylmethylamine (2.45 g) as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06172228B2
Source datasetuspto-grants-2001_01
ORD IDord-c26e0cf2cd824304818775200eedf1f3
Source noteuspto-grants-2001_01